Antagonized by CYP3A4 inducers eg, carbamazepine, rifampin. Caution with drugs that interfere with temperature regulation eg, anticholinergics. Headache, anxiety, insomnia, constipation, nausea, vomiting, somnolence, fatigue, sedation, dizziness, restlessness, akathisia, orthostatic hypotension, blurred vision, tremor, pyrexia, salivary hypersecretion, nasopharyngitis, EPS, neuroleptic malignant syndrome, tardive dyskinesia, weight gain, hyperglycemia, dyslipidemia, others.
What is this medication and its most common uses? Zofran is a medicine used to prevent nausea and vomiting associated with cancer chemotherapy, radiation treatment, and after surgery.
Zofran is available as regular tablets, orally disintegrating tablets Zofran ODTand as an oral solution. What should I know when beginning and continuing on this medication? How does this medication work? Zofran is thought to work by blocking a certain chemical in your body that may cause nausea and vomiting.
What are the beneficial effects of this medication and when should I begin to have results? Studies have shown that Zofran was effective in preventing nausea and vomiting. Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Zofran exactly as your healthcare provider has prescribed.
How do I know it is working? You may experience less nausea and vomiting while you are taking Zofran. This is a good indicator that your medicine is working. Your healthcare provider may also ask you questions from time to time to assess how well your symptoms are controlled with treatment.
What are the possible side effects of this medication?
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: Less common side effects may include: Serious allergic reactions, with symptoms such as rash; hives; itching; swelling of the face, lips, tongue, or throat; trouble breathing or swallowing; or chest tightness or pain.
Serious heart rhythm changes, with symptoms such as fast or slow heartbeat, or fainting. Serotonin syndrome a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells with symptoms such as mental status changes such as agitation or hallucinations ; a fast heartbeat; high or low blood pressure; coordination problems or muscle twitching; muscle stiffness; dizziness; flushing; tremor; seizures; or nausea, vomiting, or diarrhea.
Who should not take this medication? Do not take Zofran if you are allergic to it or any of its ingredients. Do not take Zofran if you are taking apomorphine. What should I tell my healthcare provider before I take the first dose of this medication?
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zofran. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems including abnormal heart rhythmsliver problems, phenylketonuria an inability to process phenylalanine, a protein in your bodyswelling or pain in your stomach area, low blood potassium or magnesium levels, or if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage? The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen.
Do not change the dosage or stop taking your medication without your healthcare provider's approval. Your healthcare provider will prescribe the appropriate dose for you or your child, based on the condition.A Thesis entitled The Formulation and Evaluation of Orally Disintegrating Tablets: Diphenhydramine HCl By Stephanie M.
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